2-(3-Methyl-2-nitro­phen­yl)-4,5-dihydro-1,3-oxazole

نویسندگان

  • Dongwei Lei
  • Huibin Yang
  • Bin Li
  • Zhuo Kang
چکیده

In the title compound, C(10)H(10)N(2)O(3), an inter-mediate in the synthesis of anthranilamide insecticides, all the non-H atoms except the nitro-group O atom lie on a crystallographic mirror plane. The H atoms of the methyl group are disordered over two sets of sites with equal occupancies. In the crystal structure, C-H⋯N links lead to chains of mol-ecules propagating in [100].

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منابع مشابه

2-(4,5-Dihydro-1,3-oxazol-2-yl)quinoline

The title compound, C(12)H(10)N(2)O, is approximately planar. The angle between the quinoline and 4,5-dihydro-oxazole ring systems is 11.91 (12)°. The mol-ecules pack into a herringbone array with no significant π-π inter-actions. The dihydro-oxazole N and O atoms are disordered over two positions, with almost equal site occupancy factors.

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2-(2-Methoxy­phen­yl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

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(R)-4-Phenyl-2-[(S)-1,2,3,4-tetra­hydro­isoquinolin-3-yl]-4,5-dihydro-1,3-oxazole

The asymmetric unit cell of the title compound, C(18)H(18)N(2)O, contains four molecules. In the crystal structure, an inter-molecular N-H⋯N hydrogen bond helps to establish the packing.

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Methyl 2,2′-dimethyl-4′-[2-(methyl­sulfan­yl)eth­yl]-1,3-dioxo-2,3-dihydro-1H,4′H-spiro­[isoquinoline-4,5′-oxazole]-4′-carboxyl­ate

In the isoquinoline ring system of the title mol-ecule, C(18)H(20)N(2)O(5)S, the fused N-heterocyclic ring is distorted towards a half-boat conformation. The methyl formate moiety is disordered over two sets of sites with refined occupancies of 0.882 (5) and 0.118 (5). In the crystal, mol-ecules are linked via weak inter-molecular C-H⋯O hydrogen bonds into one-dimensional chains along [010].

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Novel side reactions accompanying activation and aminolysis of N-benzoyl-2-alkylserines.

2-Phenyl-4-alkyl-4-hydroxymethyl-1,3-oxazolones (2a-d) have been identified as side products accompanying activation of N-benzoyl-2-alkylserines (1a-d). Oxazolones 2a-d in the presence of amine rearrange subsequently to corresponding 4-alkyl-2-phenyl-4,5-dihydro-1,3-oxazole-5 carboxylic acids (4a-d) at a 20-68% yield.

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عنوان ژورنال:

دوره 65  شماره 

صفحات  -

تاریخ انتشار 2008